Microbiological Transformation of Dehydroepiandrosterone, Progesterone, Desoxycorticosterone, and Testosterone by <i>Gibberella saubinetti</i>

compactifications and representations of transformation semigroups

this thesis deals essentially (but not from all aspects) with the extension of the notion of semigroup compactification and the construction of a general theory of semitopological nonaffine (affine) transformation semigroup compactifications. it determines those compactification which are universal with respect to some algebric or topological properties. as an application of the theory, it is i...

Microbiological Transformation of Terpenes

PREMA B. R. (National Chemical Laboratory, Poona, India) AND P. K. BHATTACHARYYA. Microbiological transformation of terpenes. II. Transformations of apinene. Appl. Microbiol. 10:524-528. 1962.-Several strains of fungi were tested for their ability to metabolize a-pinene in shake cultures. A strain of Aspergillus niger showing marked efficiency in this respect was selected for further studies. T...

Anti-Obesity Effects of Androgens, Dehydroepiandrosterone (DHEA) and Testosterone

Continuous microbiological transformation of steroids.

Continuous fermentation trials on the bioconversions of pregnadiene to pregnatriene by Septomyxa affinis and progesterone to 11alpha-hydroxyprogesterone by Rhizopus nigricans were conducted successfully in an eight-stage pilot plant reactor. The first stage was used as the mycelial growth stage while the steroid solutions were added continuously to stage 2, thus using the remaining stages as co...

Conversion of dehydroepiandrosterone, pregnenolone, and progesterone by interstitial cell tumor tissue.

Steroid biosynthesis was studied in a spontaneous mouse interstitial cell tumor grown as a transplant in isologous male recipients. In timed incubations the tu mor tissue rapidly transformed dehydroepiandrosterone to androstenedione. The formation of testosterone, 11/îhydroxyandrostenedione, and 11/3-hydroxytestosterone proceeded at a slower rate. A conversion product with Chromatographie char...